ABAT gene expression associated with the sensitivity of hypomethylating agents in myelodysplastic syndrome through CXCR4/mTOR signaling

Abstract The factors that affect hypomethylating agents (HMAs) sensitivity in myelodysplastic syndrome (MDS) are complex and multifaceted. They include DNA methylation, gene expression, mutation, etc. However, the underlying mechanisms are still not clearly illustrated. In the present work, ABAT gen...

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Bibliographic Details
Main Authors: Guangjie Zhao, Shuang Li, Qian Wang, Wanlin Wu, Xuewei Fu, Chen Zhu, Wei Wang, Xiaoqin Wang
Format: Article
Language:English
Published: Nature Publishing Group 2022-09-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-022-01170-7