The m6A mRNA demethylase FTO in granulosa cells retards FOS-dependent ovarian aging

The m6A mRNA demethylase FTO in granulosa cells retards FOS-dependent ovarian aging

Abstract Multifunctional N6-methyladenosine (m6A) has been revealed to be an important epigenetic component in various physiological and pathological processes, but its role in female ovarian aging remains unclear. Thus, we demonstrated m6A demethylase FTO downregulation and the ensuing increased m6...

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Bibliographic Details
Main Authors: Zhong-xin Jiang, Yi-ning Wang, Zi-yuan Li, Zhi-hui Dai, Yi He, Kun Chu, Jia-yi Gu, Yi-Xuan Ji, Ning-xia Sun, Fu Yang, Wen Li
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-04016-9

Internet

https://doi.org/10.1038/s41419-021-04016-9

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