Age and Chronodisruption in Mouse Heart: Effect of the NLRP3 Inflammasome and Melatonin Therapy

Age and Chronodisruption in Mouse Heart: Effect of the NLRP3 Inflammasome and Melatonin Therapy

Age and age-dependent inflammation are two main risk factors for cardiovascular diseases. Aging can also affect clock gene-related impairments such as chronodisruption and has been linked to a decline in melatonin synthesis and aggravation of the NF-κB/NLRP3 innate immune response known as inflammag...

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Bibliographic Details
Main Authors: Marisol Fernández-Ortiz, Ramy K. A. Sayed, Yolanda Román-Montoya, María Ángeles Rol de Lama, José Fernández-Martínez, Yolanda Ramírez-Casas, Javier Florido-Ruiz, Iryna Rusanova, Germaine Escames, Darío Acuña-Castroviejo
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:International Journal of Molecular Sciences
Subjects:
melatonin
clock genes
chronodisruption
rhythm
aging
inflammaging
Online Access:https://www.mdpi.com/1422-0067/23/12/6846

Internet

https://www.mdpi.com/1422-0067/23/12/6846

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