Jianpi-Qingchang decoction alleviates ulcerative colitis by modulating endoplasmic reticulum stress-related autophagy in intestinal epithelial cells

Jianpi-Qingchang decoction alleviates ulcerative colitis by modulating endoplasmic reticulum stress-related autophagy in intestinal epithelial cells

Endoplasmic reticulum stress (ERS)-related autophagy is involved in the occurrence and development of ulcerative colitis (UC). Therefore, regulating ERS-related autophagy is a potential therapeutic target for the treatment of UC. Jianpi-Qingchang (JPQC) decoction, consisting of nine Chinese herbal m...

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Bibliographic Details
Main Authors: Dan Qiao, Xiaoyan Liu, Yali Zhang, Ziwei Zhang, Yingjue Tang, Qian Chen, Yu Shi, Yujun Chen, Zhipeng Tang, Yancheng Dai
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Ulcerative colitis
Endoplasmic reticulum stress
Autophagy
Jianpi-Qingchang decoction
Intestinal epithelial cells
PERK-eIF2α-ATF4/Beclin1-Atg7-LC3II signaling pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332222015220

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http://www.sciencedirect.com/science/article/pii/S0753332222015220

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