Anti-Warburg effect by targeting HRD1-PFKP pathway may inhibit breast cancer progression

Anti-Warburg effect by targeting HRD1-PFKP pathway may inhibit breast cancer progression

Abstract Background Our previous studies have shown that the E3 ubiquitin ligase of HMG-CoA reductase degradation 1 (HRD1) functions as a tumor suppressor, as overexpression of HRD1 suppressed breast cancer proliferation and invasion. However, its role in breast cancer cell glucose metabolism was un...

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Bibliographic Details
Main Authors: Ya Fan, Jia Wang, Yuemei Xu, Yipin Wang, Tao Song, Xiubin Liang, Feng Jin, Dongming Su
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Cell Communication and Signaling
Subjects:
Anti-warburg effect
Cancer progression
Molecular patterns
Treatment target
Online Access:https://doi.org/10.1186/s12964-020-00679-7

Internet

https://doi.org/10.1186/s12964-020-00679-7

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