Difluorocarbene enables to access 2-fluoroindoles from ortho-vinylanilines
2-Fluoroindoles are an important structural scaffold in many bioactive or therapeutic agents, but efficient constructions of 2-fluoroindole derivatives are very sparce. Here the authors report an efficient and general strategy for the construction of 2-fluoroindoles in which a wide variety of 2-fluo...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-08-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-021-25313-z |