Difluorocarbene enables to access 2-fluoroindoles from ortho-vinylanilines

2-Fluoroindoles are an important structural scaffold in many bioactive or therapeutic agents, but efficient constructions of 2-fluoroindole derivatives are very sparce. Here the authors report an efficient and general strategy for the construction of 2-fluoroindoles in which a wide variety of 2-fluo...

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Bibliographic Details
Main Authors: Jianke Su, Xinyuan Hu, Hua Huang, Yu Guo, Qiuling Song
Format: Article
Language:English
Published: Nature Portfolio 2021-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-25313-z