Serotonin‐deficient neonatal mice are not protected against the development of experimental bronchopulmonary dysplasia or pulmonary hypertension
Abstract Serotonin (5‐hydroxytryptamine, 5‐HT) is a potent pulmonary vasoconstrictor and contributes to high pulmonary vascular resistance in the developing ovine lung. In experimental pulmonary hypertension (PH), pulmonary expression of tryptophan hydroxylase‐1 (TPH1), the rate limiting enzyme in 5...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2022-10-01
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Series: | Physiological Reports |
Subjects: | |
Online Access: | https://doi.org/10.14814/phy2.15482 |