Serotonin‐deficient neonatal mice are not protected against the development of experimental bronchopulmonary dysplasia or pulmonary hypertension

Abstract Serotonin (5‐hydroxytryptamine, 5‐HT) is a potent pulmonary vasoconstrictor and contributes to high pulmonary vascular resistance in the developing ovine lung. In experimental pulmonary hypertension (PH), pulmonary expression of tryptophan hydroxylase‐1 (TPH1), the rate limiting enzyme in 5...

Full description

Bibliographic Details
Main Authors: Danielle S. Roberts, Laura G. Sherlock, Janelle N. Posey, Jamie L. Archambault, Eva S. Nozik, Cassidy A. Delaney
Format: Article
Language:English
Published: Wiley 2022-10-01
Series:Physiological Reports
Subjects:
Online Access:https://doi.org/10.14814/phy2.15482