Alzheimer's disease/dementia-associated brain pathology in aging DPP6-KO mice

Alzheimer's disease/dementia-associated brain pathology in aging DPP6-KO mice

We have previously reported that the single transmembrane protein Dipeptidyl Peptidase Like 6 (DPP6) impacts neuronal and synaptic development. DPP6-KO mice are impaired in hippocampal-dependent learning and memory and exhibit smaller brain size. Recently, we have described novel structures in hippo...

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Bibliographic Details
Main Authors: Lin Lin, Ronald S. Petralia, Lynne Holtzclaw, Ya-Xian Wang, Daniel Abebe, Dax A. Hoffman
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:Neurobiology of Disease
Subjects:
DPP6
Alzheimer's disease
neurodegeneration
dementia
neuroinflammation
hyper-phosphorylated Tau
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996122002790

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http://www.sciencedirect.com/science/article/pii/S0969996122002790

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