Broadly neutralizing antibodies potently inhibit cell-to-cell transmission of semen leukocyte-derived SHIV162P3

Broadly neutralizing antibodies potently inhibit cell-to-cell transmission of semen leukocyte-derived SHIV162P3

Background: HIV-1 sexual transmission occurs mostly through infected semen, which contains both free virions and infected leukocytes. Transmission initiated by infected cells has been shown by several in vitro and in vivo studies and a reduced capacity of broadly neutralizing antibodies (bNAbs) to i...

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Bibliographic Details
Main Authors: Karunasinee Suphaphiphat, Monica Tolazzi, Stéphane Hua, Delphine Desjardins, Valerie Lorin, Nathalie Dereuddre-Bosquet, Hugo Mouquet, Gabriella Scarlatti, Roger Le Grand, Mariangela Cavarelli
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:EBioMedicine
Subjects:
Cell-to-cell transmission
Semen cells
bNAbs
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396420302176

Internet

http://www.sciencedirect.com/science/article/pii/S2352396420302176

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