Specific NLRP3 Inflammasome Assembling and Regulation in Neutrophils: Relevance in Inflammatory and Infectious Diseases

Specific NLRP3 Inflammasome Assembling and Regulation in Neutrophils: Relevance in Inflammatory and Infectious Diseases

The NLRP3 inflammasome is a cytosolic multimeric protein platform that leads to the activation of the protease zymogen, caspase-1 (CASP1). Inflammasome activation mediates the proteolytic activation of pro-inflammatory cytokines (IL-1β and IL-18) and program cell death called pyroptosis. The pyropto...

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Bibliographic Details
Main Authors: Christophe Paget, Emilie Doz-Deblauwe, Nathalie Winter, Benoit Briard
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Cells
Subjects:
inflammasome
neutrophils
NLRP3
caspase-1
caspase-11
IL-1β
Online Access:https://www.mdpi.com/2073-4409/11/7/1188

Internet

https://www.mdpi.com/2073-4409/11/7/1188

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