The Long Non-coding RNAs: Paramount Regulators of the NLRP3 Inflammasome

The Long Non-coding RNAs: Paramount Regulators of the NLRP3 Inflammasome

The NOD LRR pyrin domain containing protein 3 (NLRP3) inflammasome is a cytosolic multi-proteins conglomerate with intrinsic ATPase activity. Their predominant presence in the immune cells emphasizes its significant role in immune response. The downstream effector proteins IL-1β and IL-18 are respon...

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Bibliographic Details
Main Authors: Mridula P. Menon, Kuo-Feng Hua
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Immunology
Subjects:
lncRNAs
NLRP3 inflammasome
nuclear regulation
cytoplasmic regulation
chromatin remodeling
transcriptional regulation
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.569524/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.569524/full

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