Ligand-Mediated Biofilm Formation via Enhanced Physical Interaction between a Diguanylate Cyclase and Its Receptor

Ligand-Mediated Biofilm Formation via Enhanced Physical Interaction between a Diguanylate Cyclase and Its Receptor

ABSTRACT The bacterial intracellular second messenger, cyclic dimeric GMP (c-di-GMP), regulates biofilm formation for many bacteria. The binding of c-di-GMP by the inner membrane protein LapD controls biofilm formation, and the LapD receptor is central to a complex network of c-di-GMP-mediated biofi...

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Bibliographic Details
Main Authors: David Giacalone, T. Jarrod Smith, Alan J. Collins, Holger Sondermann, Lori J. Koziol, George A. O’Toole
Format: Article
Language:English
Published: American Society for Microbiology 2018-09-01
Series:mBio
Subjects:
CACHE domain
Pseudomonas fluorescens
biofilm
c-di-GMP
receptor
signaling
Online Access:https://journals.asm.org/doi/10.1128/mBio.01254-18

Internet

https://journals.asm.org/doi/10.1128/mBio.01254-18

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