A novel autophagy enhancer as a therapeutic agent against metabolic syndrome and diabetes
Autophagy plays an important role in metabolic functions and increased autophagic activity may be beneficial for metabolic disorders. Here the authors screen a chemical library for enhancer of autophagic flux and identify small molecules that improve the metabolic profile by increasing lysosomial fu...
Main Authors: | , , , , , , , , , , , |
---|---|
格式: | Article |
語言: | English |
出版: |
Nature Portfolio
2018-04-01
|
叢編: | Nature Communications |
在線閱讀: | https://doi.org/10.1038/s41467-018-03939-w |