A novel autophagy enhancer as a therapeutic agent against metabolic syndrome and diabetes

Autophagy plays an important role in metabolic functions and increased autophagic activity may be beneficial for metabolic disorders. Here the authors screen a chemical library for enhancer of autophagic flux and identify small molecules that improve the metabolic profile by increasing lysosomial fu...

全面介绍

书目详细资料
Main Authors: Hyejin Lim, Yu-Mi Lim, Kook Hwan Kim, Young Eui Jeon, Kihyoun Park, Jinyoung Kim, Hui-Yun Hwang, Dong Jin Lee, Haushabhau Pagire, Ho Jeong Kwon, Jin Hee Ahn, Myung-Shik Lee
格式: 文件
语言:English
出版: Nature Portfolio 2018-04-01
丛编:Nature Communications
在线阅读:https://doi.org/10.1038/s41467-018-03939-w
实物特征
总结:Autophagy plays an important role in metabolic functions and increased autophagic activity may be beneficial for metabolic disorders. Here the authors screen a chemical library for enhancer of autophagic flux and identify small molecules that improve the metabolic profile by increasing lysosomial functions.
ISSN:2041-1723