IL-10−/− Enhances DCs Immunity Against Chlamydia psittaci Infection via OX40L/NLRP3 and IDO/Treg Pathways

IL-10−/− Enhances DCs Immunity Against Chlamydia psittaci Infection via OX40L/NLRP3 and IDO/Treg Pathways

Chlamydia psittaci (C. psittaci) is a common zoonotic agent that affects both poultry and humans. Interleukin 10 (IL-10) is an anti-inflammatory factor produced during chlamydial infection, while dendritic cells (DCs) are powerful antigen-presenting cells that induce a primary immune response in the...

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Bibliographic Details
Main Authors: Qiang Li, Xiaohui Li, Hongkun Quan, Yihui Wang, Guanggang Qu, Zhiqiang Shen, Cheng He
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Immunology
Subjects:
Chlamydia psittaci
interleukin-10
dendritic cells
OX40-OX40L
NLRP3 inflammasome
apoptosis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.645653/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.645653/full

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