3D bioprinted multilayered cerebrovascular conduits to study cancer extravasation mechanism related with vascular geometry
Abstract Cerebral vessels are composed of highly complex structures that facilitate blood perfusion necessary for meeting the high energy demands of the brain. Their geometrical complexities alter the biophysical behavior of circulating tumor cells in the brain, thereby influencing brain metastasis....
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-11-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-023-43586-4 |