The Impact of Muscarinic Antagonism on Psychosis-Relevant Behaviors and Striatal [<sup>11</sup>C] Raclopride Binding in Tau Mouse Models of Alzheimer’s Disease

The Impact of Muscarinic Antagonism on Psychosis-Relevant Behaviors and Striatal [<sup>11</sup>C] Raclopride Binding in Tau Mouse Models of Alzheimer’s Disease

Psychosis that occurs over the course of Alzheimer’s disease (AD) is associated with increased caregiver burden and a more rapid cognitive and functional decline. To find new treatment targets, studies modeling psychotic conditions traditionally employ agents known to induce psychosis, utilizing out...

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Bibliographic Details
Main Authors: Heidy Jimenez, Joseph Carrion, Leslie Adrien, Adam Wolin, John Eun, Ezra Cinamon, Eric H. Chang, Peter Davies, An Vo, Jeremy Koppel
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Biomedicines
Subjects:
tau
psychosis
scopolamine
locomotion
Alzheimer’s disease
hopping
Online Access:https://www.mdpi.com/2227-9059/11/8/2091

Internet

https://www.mdpi.com/2227-9059/11/8/2091

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