Analysis of nucleic acids extracted from rapid diagnostic tests reveals a significant proportion of false positive test results associated with recent malaria treatment

Analysis of nucleic acids extracted from rapid diagnostic tests reveals a significant proportion of false positive test results associated with recent malaria treatment

Abstract Background Surveillance programmes often use malaria rapid diagnostic tests (RDTs) to determine the proportion of the population carrying parasites in their peripheral blood to assess the malaria transmission intensity. Despite an increasing number of reports on false-negative and false-pos...

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Bibliographic Details
Main Authors: Salome Hosch, Charlene Aya Yoboue, Olivier Tresor Donfack, Etienne A. Guirou, Jean-Pierre Dangy, Maxmillian Mpina, Elizabeth Nyakurungu, Koranan Blöchliger, Carlos A. Guerra, Wonder P. Phiri, Mitoha Ondo’o Ayekaba, Guillermo A. García, Marcel Tanner, Claudia Daubenberger, Tobias Schindler
Format: Article
Language:English
Published: BMC 2022-01-01
Series:Malaria Journal
Subjects:
Molecular malaria surveillance
False-positive malaria rapid diagnostic test
PfHRP2 persistence
pfhrp2 gene deletion
Online Access:https://doi.org/10.1186/s12936-022-04043-7

Internet

https://doi.org/10.1186/s12936-022-04043-7

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