ANRIL Promoter DNA Methylation: A Perinatal Marker for Later Adiposity

ANRIL Promoter DNA Methylation: A Perinatal Marker for Later Adiposity

Experimental studies show a substantial contribution of early life environment to obesity risk through epigenetic processes. We examined inter-individual DNA methylation differences in human birth tissues associated with child's adiposity. We identified a novel association between the level of...

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Bibliographic Details
Main Authors: Karen Lillycrop, Robert Murray, Clara Cheong, Ai Ling Teh, Rebecca Clarke-Harris, Sheila Barton, Paula Costello, Emma Garratt, Eloise Cook, Philip Titcombe, Bhuvaneshwari Shunmuganathan, Samantha J. Liew, Yong-Cai Chua, Xinyi Lin, Yonghui Wu, Graham C. Burdge, Cyrus Cooper, Hazel M. Inskip, Neerja Karnani, James C. Hopkins, Caroline E. Childs, Carolina Paras Chavez, Philip C. Calder, Fabian Yap, Yung Seng Lee, Yap Seng Chong, Philip E. Melton, Lawrie Beilin, Rae-Chi Huang, Peter D. Gluckman, Nick Harvey, Mark A. Hanson, Joanna D. Holbrook, Keith M. Godfrey
Format: Article
Language:English
Published: Elsevier 2017-05-01
Series:EBioMedicine
Subjects:
DNA methylation
Adiposity
Epigenetic
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396417301330

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http://www.sciencedirect.com/science/article/pii/S2352396417301330

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