Cis-activation in the Notch signaling pathway
The Notch signaling pathway consists of transmembrane ligands and receptors that can interact both within the same cell (cis) and across cell boundaries (trans). Previous work has shown that cis-interactions act to inhibit productive signaling. Here, by analyzing Notch activation in single cells whi...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2019-01-01
|
Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/37880 |