L-Form Switching in Escherichia coli as a Common β-Lactam Resistance Mechanism

L-Form Switching in Escherichia coli as a Common β-Lactam Resistance Mechanism

ABSTRACT Cell wall deficient bacterial L-forms are induced by exposure to cell wall-targeting antibiotics and immune effectors such as lysozyme. L-forms of different bacteria (including Escherichia coli) have been reported in human infections, but whether this is a normal adaptive strategy or simply...

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Bibliographic Details
Main Authors: Aleksandra Petrovic Fabijan, David Martinez-Martin, Carola Venturini, Katarzyna Mickiewicz, Neftali Flores-Rodriguez, Jeff Errington, Jonathan Iredell
Format: Article
Language:English
Published: American Society for Microbiology 2022-10-01
Series:Microbiology Spectrum
Subjects:
L-forms
β-lactams
refractory infections
Escherichia coli
antibiotic resistance
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02419-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.02419-22

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