Combined Therapy with Dacarbazine and Hyperthermia Induces Cytotoxicity in A375 and MNT-1 Melanoma Cells

Combined Therapy with Dacarbazine and Hyperthermia Induces Cytotoxicity in A375 and MNT-1 Melanoma Cells

Melanoma is a drug-resistant cancer, representing a serious challenge in cancer treatment. Dacarbazine (DTIC) is the standard drug in metastatic melanoma treatment, despite the poor results. Hyperthermia has been proven to potentiate chemotherapy. Hence, this work analyzed the combined action of hyp...

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Bibliographic Details
Main Authors: Diana Salvador, Verónica Bastos, Helena Oliveira
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:International Journal of Molecular Sciences
Subjects:
melanoma
low-dose chemotherapy
mild hyperthermia
cytotoxicity
cell cycle
Online Access:https://www.mdpi.com/1422-0067/23/7/3586

Internet

https://www.mdpi.com/1422-0067/23/7/3586

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