A transient increase of HIF-1α during the G1 phase (G1-HIF) ensures cell survival under nutritional stress

A transient increase of HIF-1α during the G1 phase (G1-HIF) ensures cell survival under nutritional stress

Abstract The family of hypoxia-inducible transcription factors (HIF) is activated to adapt cells to low oxygen conditions, but is also known to regulate some biological processes under normoxic conditions. Here we show that HIF-1α protein levels transiently increase during the G1 phase of the cell c...

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Bibliographic Details
Main Authors: Ratnal Belapurkar, Maximilian Pfisterer, Jan Dreute, Sebastian Werner, Sven Zukunft, Ingrid Fleming, Michael Kracht, M. Lienhard SCHMITZ
Format: Article
Language:English
Published: Nature Publishing Group 2023-07-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-06012-7

Internet

https://doi.org/10.1038/s41419-023-06012-7

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