Insertion of a Suicide Gene into an Immortalized Human Hepatocyte Cell Line

For developing a bioartificial liver (BAL) device, an attractive alternative to the primary human hepatocytes would be the use of highly differentiated immortalized human hepatocytes with a safeguard. To test the feasibility, the primary human hepatocytes were immortalized by a plasmid SV3neo encodi...

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Main Authors: Naoya Kobayashi M.D., Ph.D., Hirofumi Noguchi, Toshinori Totsugawa, Takamasa Watanabe, Toshihisa Matsumura, Toshiyoshi Fujiwara, Masahiro Miyazaki, Kenichi Fukaya, Masayoshi Namba, Noriaki Tanaka
Format: Article
Language:English
Published: SAGE Publishing 2001-05-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/000000001783986648