Encapsulation of SAAP-148 in Octenyl Succinic Anhydride-Modified Hyaluronic Acid Nanogels for Treatment of Skin Wound Infections

Encapsulation of SAAP-148 in Octenyl Succinic Anhydride-Modified Hyaluronic Acid Nanogels for Treatment of Skin Wound Infections

Chronic wound infections colonized by bacteria are becoming more difficult to treat with current antibiotics due to the development of antimicrobial resistance (AMR) as well as biofilm and persister cell formation. Synthetic antibacterial and antibiofilm peptide (SAAP)-148 is an excellent alternativ...

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Bibliographic Details
Main Authors: Miriam E. van Gent, Tom van Baaren, Sylvia N. Kłodzińska, Muhanad Ali, Natasja Dolezal, Bjorn R. van Doodewaerd, Erik Bos, Amy M. de Waal, Roman I. Koning, Jan Wouter Drijfhout, Hanne Mørck Nielsen, Peter H. Nibbering
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Pharmaceutics
Subjects:
antimicrobial peptide
SAAP-148
hyaluronic acid-based nanogels
AMP formulation
skin wound infections
cutaneous application
Online Access:https://www.mdpi.com/1999-4923/15/2/429

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https://www.mdpi.com/1999-4923/15/2/429

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