Development and characterization of DIA 12.3, a fully human intact anti-CEACAM1 monoclonal antibody.

Development and characterization of DIA 12.3, a fully human intact anti-CEACAM1 monoclonal antibody.

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Carcinoembryonic antigen cell adhesion molecule-1 (CEACAM1), a homotypic cell adhesion molecule glycoprotein with apical expression on normal epithelial cells and activated lymphocytes, is overexpressed on many tumors and acts as an inhibitory receptor on NK cells, preventing their killing of CEACAM...

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Bibliographic Details
Main Authors: Michela Centonze, Valentina Fiori, Maciej Kujawski, Lin Li, Patty Wong, Lindsay Williams, Tomas Di Mambro, Sabrina Dominici, Angelo Sparti, John E Shively, Mauro Magnani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0295345&type=printable

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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0295345&type=printable

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