Quantitative analysis of how Myc controls T cell proteomes and metabolic pathways during T cell activation

T cell expansion and differentiation are critically dependent on the transcription factor c-Myc (Myc). Herein we use quantitative mass-spectrometry to reveal how Myc controls antigen receptor driven cell growth and proteome restructuring in murine T cells. Analysis of copy numbers per cell of &g...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Julia M Marchingo, Linda V Sinclair, Andrew JM Howden, Doreen A Cantrell
Μορφή: Άρθρο
Γλώσσα:English
Έκδοση: eLife Sciences Publications Ltd 2020-02-01
Σειρά:eLife
Θέματα:
Διαθέσιμο Online:https://elifesciences.org/articles/53725