Quantitative analysis of how Myc controls T cell proteomes and metabolic pathways during T cell activation

T cell expansion and differentiation are critically dependent on the transcription factor c-Myc (Myc). Herein we use quantitative mass-spectrometry to reveal how Myc controls antigen receptor driven cell growth and proteome restructuring in murine T cells. Analysis of copy numbers per cell of &g...

詳細記述

書誌詳細
主要な著者: Julia M Marchingo, Linda V Sinclair, Andrew JM Howden, Doreen A Cantrell
フォーマット: 論文
言語:English
出版事項: eLife Sciences Publications Ltd 2020-02-01
シリーズ:eLife
主題:
オンライン・アクセス:https://elifesciences.org/articles/53725