Quantitative analysis of how Myc controls T cell proteomes and metabolic pathways during T cell activation
T cell expansion and differentiation are critically dependent on the transcription factor c-Myc (Myc). Herein we use quantitative mass-spectrometry to reveal how Myc controls antigen receptor driven cell growth and proteome restructuring in murine T cells. Analysis of copy numbers per cell of &g...
Main Authors: | , , , |
---|---|
格式: | 文件 |
语言: | English |
出版: |
eLife Sciences Publications Ltd
2020-02-01
|
丛编: | eLife |
主题: | |
在线阅读: | https://elifesciences.org/articles/53725 |