Dry Amorphization of Itraconazole Using Mesoporous Silica and Twin-Screw Technology

<b>Background/Objectives:</b> Amorphization of an active pharmaceutical ingredient (API) can improve its dissolution and enhance bioavailability. Avoiding solvents for drug amorphization is beneficial due to environmental issues and potential solvent residues in the final product. <b&...

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Автори: Margarethe Richter, Simon Welzmiller, Fred Monsuur, Annika R. Völp, Joachim Quadflieg
Формат: Стаття
Мова:English
Опубліковано: MDPI AG 2024-10-01
Серія:Pharmaceutics
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Онлайн доступ:https://www.mdpi.com/1999-4923/16/11/1368