Dry Amorphization of Itraconazole Using Mesoporous Silica and Twin-Screw Technology

Dry Amorphization of Itraconazole Using Mesoporous Silica and Twin-Screw Technology

<b>Background/Objectives:</b> Amorphization of an active pharmaceutical ingredient (API) can improve its dissolution and enhance bioavailability. Avoiding solvents for drug amorphization is beneficial due to environmental issues and potential solvent residues in the final product. <b&...

Deskribapen osoa

Xehetasun bibliografikoak
Egile Nagusiak: Margarethe Richter, Simon Welzmiller, Fred Monsuur, Annika R. Völp, Joachim Quadflieg
Formatua: Artikulua
Hizkuntza:English
Argitaratua: MDPI AG 2024-10-01
Saila:Pharmaceutics
Gaiak:
twin-screw granulation
twin-screw extruder
API amorphization
solubility enhancement
mesoporous silica
continuous manufacturing
Sarrera elektronikoa:https://www.mdpi.com/1999-4923/16/11/1368

Internet

https://www.mdpi.com/1999-4923/16/11/1368

Antzeko izenburuak