Compromised endothelial Wnt/β-catenin signaling mediates the blood-brain barrier disruption and leads to neuroinflammation in endotoxemia

Compromised endothelial Wnt/β-catenin signaling mediates the blood-brain barrier disruption and leads to neuroinflammation in endotoxemia

Abstract The blood-brain barrier (BBB) is a critical interface that maintains the central nervous system homeostasis by controlling the exchange of substances between the blood and the brain. Disruption of the BBB plays a vital role in the development of neuroinflammation and neurological dysfunctio...

Deskribapen osoa

Xehetasun bibliografikoak
Egile Nagusiak: Xiaowen Huang, Pengju Wei, Cheng Fang, Min Yu, Shilun Yang, Linhui Qiu, Yu Wang, Aimin Xu, Ruby Lai Chong Hoo, Junlei Chang
Formatua: Artikulua
Hizkuntza:English
Argitaratua: BMC 2024-10-01
Saila:Journal of Neuroinflammation
Gaiak:
Endotoxemia
Blood-brain barrier
Neuroinflammation
Wnt/β-catenin signaling
NF-κB pathway
Sarrera elektronikoa:https://doi.org/10.1186/s12974-024-03261-x

Internet

https://doi.org/10.1186/s12974-024-03261-x

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