Epigenetic Modifications: Therapeutic Potential in Cancer

Epigenetic Modifications: Therapeutic Potential in Cancer

Epigenetic modifications and alterations in chromatin structure and function contribute to the cumulative changes observed as normal cells undergo malignant transformation. These modifications and enzymes (DNA methyltransferases, histone deacetylases, histone methyltransferases, and demethylases) re...

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Bibliographic Details
Main Authors: Manisha Sachan, Manpreet Kaur
Format: Article
Language:English
Published: Instituto de Tecnologia do Paraná (Tecpar) 2015-08-01
Series:Brazilian Archives of Biology and Technology
Subjects:
HDAC inhibitors
Cancer epigenetics
Histone modification
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132015000400526&lng=en&tlng=en

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