Epigenetic Modifications: Therapeutic Potential in Cancer

Epigenetic Modifications: Therapeutic Potential in Cancer

Epigenetic modifications and alterations in chromatin structure and function contribute to the cumulative changes observed as normal cells undergo malignant transformation. These modifications and enzymes (DNA methyltransferases, histone deacetylases, histone methyltransferases, and demethylases) re...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид:	Manisha Sachan, Manpreet Kaur
Формат:	Өгүүллэг
Хэл сонгох:	English
Хэвлэсэн:	Instituto de Tecnologia do Paraná (Tecpar) 2015-08-01
Цуврал:	Brazilian Archives of Biology and Technology
Нөхцлүүд:	HDAC inhibitors Cancer epigenetics Histone modification
Онлайн хандалт:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132015000400526&lng=en&tlng=en

Ижил төстэй зүйлс

Epigenetic Modifications in Alzheimer’s Neuropathology and Therapeutics
-н: Michelle Esposito, зэрэг
Хэвлэсэн: (2019-05-01)

The Roles of Histone Deacetylases and Their Inhibitors in Cancer Therapy
-н: Guo Li, зэрэг
Хэвлэсэн: (2020-09-01)

Implication des modifications épigénétiques dans les cancers : développement de nouvelles approches thérapeutiques
-н: Willems L., зэрэг
Хэвлэсэн: (2008-01-01)

Hedgehog pathway orchestrates the interplay of histone modifications and tailors combination epigenetic therapies in breast cancer
-н: Xiaomin Wang, зэрэг
Хэвлэсэн: (2023-06-01)

Roles of histone deacetylases in epigenetic regulation: emerging paradigms from studies with inhibitors
-н: Delcuve Geneviève P, зэрэг
Хэвлэсэн: (2012-03-01)

The therapeutic potential of class I selective histone deacetylase inhibitors in ovarian cancer
-н: Dineo eKhabele
Хэвлэсэн: (2014-05-01)

dCas9-HDAC8-EGFP fusion enables epigenetic editing of breast cancer cells by H3K9 deacetylation
-н: Mohammad Mijanur Rahman, зэрэг
Хэвлэсэн: (2024-12-01)

Interaction of ncRNA and Epigenetic Modifications in Gastric Cancer: Focus on Histone Modification
-н: Qingfan Yang, зэрэг
Хэвлэсэн: (2022-01-01)

Epigenetic regulation by gut microbiota
-н: Vivienne Woo, зэрэг
Хэвлэсэн: (2022-12-01)

Epigenetic modification enzymes: catalytic mechanisms and inhibitors
-н: Duo Lu
Хэвлэсэн: (2013-05-01)

Targeting Histone Deacetylases: Opportunities for Cancer Treatment and Chemoprevention
-н: Dusan Ruzic, зэрэг
Хэвлэсэн: (2022-01-01)

Epigenetic control of the vicious cycle
-н: Madeline B. Searcy, зэрэг
Хэвлэсэн: (2024-02-01)

The role of HDAC3 in inflammation: mechanisms and therapeutic implications
-н: Noah Watson, зэрэг
Хэвлэсэн: (2024-07-01)

The Emerging Roles and Therapeutic Implications of Epigenetic Modifications in Ovarian Cancer
-н: Yu Wang, зэрэг
Хэвлэсэн: (2022-05-01)

Epigenetics in Inflammatory Breast Cancer: Biological Features and Therapeutic Perspectives
-н: Flavia Lima Costa Faldoni, зэрэг
Хэвлэсэн: (2020-05-01)

Reciprocal Regulation of Metabolic Reprogramming and Epigenetic Modifications in Cancer
-н: Xilan Yu, зэрэг
Хэвлэсэн: (2018-09-01)

Histones and their modifications in ovarian cancer – drivers of disease and therapeutic targets
-н: Deborah Joy Marsh, зэрэг
Хэвлэсэн: (2014-06-01)

EPIGENETIC EFFECTS OF ENZASTAURIN – A NEW ASPECT IN THE MECHANISM OF ACTION OF AN ANTICANCER DRUG FROM PROTEIN KINASE INHIBITORS
-н: V. P. Maksimova, зэрэг
Хэвлэсэн: (2020-09-01)

From Bench to Bedside: Targeting Epigenetics for Cancer Therapy
-н: Jin-xu Fang, зэрэг
Хэвлэсэн: (2011-12-01)

Mechanisms and technologies in cancer epigenetics
-н: Zaki A. Sherif, зэрэг
Хэвлэсэн: (2025-01-01)

Histone Deacetylases and their Inhibitors in Cancer Epigenetics
-н: Kelly N. Hassell
Хэвлэсэн: (2019-11-01)

Cellular Epigenetic Targets and Epidrugs in Breast Cancer Therapy: Mechanisms, Challenges, and Future Perspectives
-н: Ibrahim S. Alalhareth, зэрэг
Хэвлэсэн: (2025-02-01)

Histone deacetylase inhibition leads to regulatory histone mark alterations and impairs meiosis in oocytes
-н: Louis Legoff, зэрэг
Хэвлэсэн: (2021-08-01)

Epigenetic modifications: Key players in cancer heterogeneity and drug resistance
-н: Hana Q. Sadida, зэрэг
Хэвлэсэн: (2024-01-01)

The proteasome and epigenetics: zooming in on histone modifications
-н: Bach Svitlana V., зэрэг
Хэвлэсэн: (2016-08-01)

New Insight in HDACs: Potential Therapeutic Targets for the Treatment of Atherosclerosis
-н: Yi Luan, зэрэг
Хэвлэсэн: (2022-04-01)

Epigenetics modifications and therapeutic prospects in human thyroid cancer
-н: Maria Graziella eCatalano, зэрэг
Хэвлэсэн: (2012-03-01)

Histone deacetylases and their inhibitors: molecular mechanisms and therapeutic implications in diabetes mellitus
-н: Xiaojie Wang, зэрэг
Хэвлэсэн: (2012-08-01)

Metabolism and Epigenetic Interplay in Cancer: Regulation and Putative Therapeutic Targets
-н: Vera Miranda-Gonçalves, зэрэг
Хэвлэсэн: (2018-10-01)

Connections between metabolism and epigenetic modifications in cancer
-н: Wang Guangchao, зэрэг
Хэвлэсэн: (2021-12-01)

Small-Molecule Inhibitors Overcome Epigenetic Reprogramming for Cancer Therapy
-н: Wenjing Xiao, зэрэг
Хэвлэсэн: (2021-09-01)

Drugs Targeting Epigenetic Modifications and Plausible Therapeutic Strategies Against Colorectal Cancer
-н: Srinivas Patnaik, зэрэг
Хэвлэсэн: (2019-06-01)

Human iPSC-Cardiomyocytes as an Experimental Model to Study Epigenetic Modifiers of Electrophysiology
-н: Maria R. Pozo, зэрэг
Хэвлэсэн: (2022-01-01)

Corrigendum: Metabolism and Epigenetic Interplay in Cancer: Regulation and Putative Therapeutic Targets
-н: Vera Miranda-Gonçalves, зэрэг
Хэвлэсэн: (2019-09-01)

Intersection of Epigenetic and Metabolic Regulation of Histone Modifications in Acute Myeloid Leukemia
-н: Abhinav Dhall, зэрэг
Хэвлэсэн: (2019-05-01)

Deciphering the potential role of post-translational modifications of histones in gastrointestinal cancers: a proteomics-based review with therapeutic challenges and opportunities
-н: Reyhaneh Farrokhi Yekta, зэрэг
Хэвлэсэн: (2024-10-01)

Role of Epigenetic Modifications in Inhibitory Immune Checkpoints in Cancer Development and Progression
-н: Reem Saleh, зэрэг
Хэвлэсэн: (2020-07-01)

Epigenetic Modifications of Host Genes Induced by Bacterial Infection
-н: Maryam Parhamfar, зэрэг
Хэвлэсэн: (2021-08-01)

NSD family proteins: Rising stars as therapeutic targets
-н: Lin He, зэрэг
Хэвлэсэн: (2024-04-01)

Pulmonary Pathogen-Induced Epigenetic Modifications
-н: Dylan Wrede, зэрэг
Хэвлэсэн: (2023-07-01)