Epigenetic Modifications: Therapeutic Potential in Cancer

Epigenetic modifications and alterations in chromatin structure and function contribute to the cumulative changes observed as normal cells undergo malignant transformation. These modifications and enzymes (DNA methyltransferases, histone deacetylases, histone methyltransferases, and demethylases) re...

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Hlavní autoři: Manisha Sachan, Manpreet Kaur
Médium: Článek
Jazyk:English
Vydáno: Instituto de Tecnologia do Paraná (Tecpar) 2015-08-01
Edice:Brazilian Archives of Biology and Technology
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On-line přístup:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132015000400526&lng=en&tlng=en