Targeted Expression to Liver of an antimiR-33 Sponge as a Gene Therapy Strategy against Hypercholesterolemia: In Vitro Study

Targeted Expression to Liver of an antimiR-33 Sponge as a Gene Therapy Strategy against Hypercholesterolemia: In Vitro Study

Atherosclerosis is the leading cause of cardiovascular diseases in Mexico and worldwide. The membrane transporters ABCA1 and ABCG1 are involved in the reverse transport of cholesterol and stimulate the HDL synthesis in hepatocytes, therefore the deficiency of these transporters promotes the accelera...

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Bibliographic Details
Main Authors: Mariela Montaño-Samaniego, Jorge Sánchez-Cedillo, Amellalli Lucas-González, Diana M. Bravo-Estupiñan, Ernesto Alarcón-Hernández, Sandra Rivera-Gutiérrez, José Abraham Balderas-López, Miguel Ibáñez-Hernández
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Current Issues in Molecular Biology
Subjects:
atherosclerosis
gene therapy
antimiR-33 sponge
ABCA1 and ABCG1 transporters
Online Access:https://www.mdpi.com/1467-3045/45/9/445

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https://www.mdpi.com/1467-3045/45/9/445

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