Transgenerational epigenetic programming of the brain transcriptome and anxiety behavior.

Transgenerational epigenetic programming of the brain transcriptome and anxiety behavior.

Embryonic exposure to the endocrine disruptor vinclozolin during gonadal sex determination promotes an epigenetic reprogramming of the male germ-line that is associated with transgenerational adult onset disease states. Further analysis of this transgenerational phenotype on the brain demonstrated r...

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Bibliographic Details
Main Authors: Michael K Skinner, Matthew D Anway, Marina I Savenkova, Andrea C Gore, David Crews
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2581440?pdf=render

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http://europepmc.org/articles/PMC2581440?pdf=render

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