Modifier genes and Lynch syndrome: some considerations
Abstract Lynch Syndrome (LS) is a highly variable entity with some patients presenting at very young ages with malignancy whereas others may never develop a malignancy yet carry an unequivocal genetic predisposition to disease. The most frequent LS malignancy remains colorectal cancer, a disease tha...
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Format: | Article |
Language: | English |
Published: |
BMC
2022-09-01
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Series: | Hereditary Cancer in Clinical Practice |
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Online Access: | https://doi.org/10.1186/s13053-022-00240-2 |