Modifier genes and Lynch syndrome: some considerations

Abstract Lynch Syndrome (LS) is a highly variable entity with some patients presenting at very young ages with malignancy whereas others may never develop a malignancy yet carry an unequivocal genetic predisposition to disease. The most frequent LS malignancy remains colorectal cancer, a disease tha...

Full description

Bibliographic Details
Main Author: Rodney J. Scott
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Hereditary Cancer in Clinical Practice
Subjects:
Online Access:https://doi.org/10.1186/s13053-022-00240-2