TMC7 functions as a suppressor of Piezo2 in primary sensory neurons blunting peripheral mechanotransduction

TMC7 functions as a suppressor of Piezo2 in primary sensory neurons blunting peripheral mechanotransduction

Summary: The transmembrane channel-like (TMC) protein family comprises eight members, with TMC1 and TMC2 being extensively studied. This study demonstrates substantial co-expression of TMC7 with the mechanosensitive channel Piezo2 in somatosensory neurons. Genetic deletion of TMC7 in primary sensory...

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Bibliographic Details
Main Authors: Xiaoxue Zhang, Jichen Shao, Caixue Wang, Chao Liu, Han Hao, Xinmeng Li, Yating An, Jinsha He, Weixin Zhao, Yiwen Zhao, Youzhen Kong, Zhanfeng Jia, Shaopo Wan, Yi Yuan, Huiran Zhang, Hailin Zhang, Xiaona Du
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Cell Reports
Subjects:
CP: Neuroscience
CP: Molecular biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724003425

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http://www.sciencedirect.com/science/article/pii/S2211124724003425

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