Two apolipoprotein E5 variants illustrate the importance of the position of additional positive charge on receptor-binding activity

Apolipoprotein (apo) E polymorphism has a significant effect on plasma cholesterol and low density lipoprotein cholesterol concentrations. The association of two apoE5 isoforms with elevated plasma low density lipoprotein cholesterol levels in two unrelated subjects led us to investigate the primary...

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Bibliographic Details
Main Authors: MR Wardell, SC Rall, Jr, EJ Schaefer, JP Kane, KH Weisgraber
Format: Article
Language:English
Published: Elsevier 1991-03-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520420760