Two apolipoprotein E5 variants illustrate the importance of the position of additional positive charge on receptor-binding activity
Apolipoprotein (apo) E polymorphism has a significant effect on plasma cholesterol and low density lipoprotein cholesterol concentrations. The association of two apoE5 isoforms with elevated plasma low density lipoprotein cholesterol levels in two unrelated subjects led us to investigate the primary...
Main Authors: | MR Wardell, SC Rall, Jr, EJ Schaefer, JP Kane, KH Weisgraber |
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Format: | Article |
Language: | English |
Published: |
Elsevier
1991-03-01
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Series: | Journal of Lipid Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520420760 |
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