Molecular Evolution of MDM1, a "Duplication-Resistant" Gene in Vertebrates.
The mouse double minute 1 (Mdm1) gene was first reported and cloned in mouse tumor cell lines as an oncogene candidate. Later, it was found that mutation of Mdm1 might cause age-related retinal degeneration 2 in mice by genetic linkage analysis. Additionally, the MDM1 protein was found to be express...
Main Authors: | Monica R Hensley, Rhys F M Chua, Yuk Fai Leung, Jer-Yen Yang, GuangJun Zhang |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2016-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC5033493?pdf=render |
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