An Overview of the Use of Anti-Angiogenic Agents in the Treatment of Thymic Epithelial Tumors

Angiogenesis significantly influences the carcinogenesis of thymic epithelial tumors (TET). Both thymomas and thymic carcinoma (TC) overexpress VEGF-A and VEGFR-1 and -2. This review aims to provide an appraisal of the use of anti-angiogenics in the treatment of TET. The literature research identifi...

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Bibliographic Details
Main Authors: Apostolos C. Agrafiotis, Lawek Berzenji, Stien Koyen, Dries Vermeulen, Rachel Winthagen, Jeroen M. H. Hendriks, Paul E. Van Schil
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/24/23/17065