High‐Resolution Transthoracic Echocardiography Accurately Detects Pulmonary Arterial Pressure and Decreased Right Ventricular Contractility in a Mouse Model of Pulmonary Fibrosis and Secondary Pulmonary Hypertension

High‐Resolution Transthoracic Echocardiography Accurately Detects Pulmonary Arterial Pressure and Decreased Right Ventricular Contractility in a Mouse Model of Pulmonary Fibrosis and Secondary Pulmonary Hypertension

Background To date, assessment of right ventricular (RV) function in mice has relied extensively on invasive measurements. Echocardiographic advances have allowed adaptation of measures used in humans for serial, noninvasive RV functional assessment in mice. We evaluated the diagnostic performance o...

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Bibliographic Details
Main Authors: Thomas S. Hansen, Kristen J. Bubb, Gabriele G. Schiattarella, Martin Ugander, Timothy C. Tan, Gemma A. Figtree
Format: Article
Language:English
Published: Wiley 2022-12-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
bleomycin
echocardiography
mouse model
pulmonary hypertension
right ventricle
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.120.018353

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.120.018353

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