Obesity impacts placental function through activation of p-IRE1a-XBP1s signaling

Maternal obesity is associated with a variety of obstetrical outcomes including stillbirth, preeclampsia, and gestational diabetes, and increases the risk of fetuses for congenital heart defects. Obesity during pregnancy represents a major contribution to metabolic dysregulation, which not only play...

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Bibliographic Details
Main Authors: Wei-Bin Shen, Bingbing Wang, Ruofan Yao, Katherine R. Goetzinger, Sheng Wu, Haijun Gao, Peixin Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1023327/full