Evaluating feature extraction in ovarian cancer cell line co-cultures using deep neural networks

Abstract Single-cell image analysis is crucial for studying drug effects on cellular morphology and phenotypic changes. Most studies focus on single cell types, overlooking the complexity of cellular interactions. Here, we establish an analysis pipeline to extract phenotypic features of cancer cells...

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Bibliographic Details
Main Authors: Osheen Sharma, Greta Gudoityte, Rezan Minozada, Olli P. Kallioniemi, Riku Turkki, Lassi Paavolainen, Brinton Seashore-Ludlow
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-07766-w