Antioxidant Properties of Zinc and Copper—Blood Zinc-to Copper-Ratio as a Marker of Cancer Risk BRCA1 Mutation Carriers

Antioxidant Properties of Zinc and Copper—Blood Zinc-to Copper-Ratio as a Marker of Cancer Risk BRCA1 Mutation Carriers

Pathogenic mutations in BRCA1 (BReast CAncer gene 1) confer high risks of both breast (up to 70%) and ovarian (up to 40%) cancers. Zinc (Zn) and copper (Cu) are essential for various physiological functions, including antioxidant reactions. Their balance, reflected in the Zn/Cu ratio, plays a crucia...

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Bibliographic Details
Main Authors: Milena Matuszczak, Adam Kiljańczyk, Wojciech Marciniak, Róża Derkacz, Klaudia Stempa, Piotr Baszuk, Marta Bryśkiewicz, Cezary Cybulski, Tadeusz Dębniak, Jacek Gronwald, Tomasz Huzarski, Marcin Lener, Anna Jakubowska, Marek Szwiec, Małgorzata Stawicka-Niełacna, Dariusz Godlewski, Artur Prusaczyk, Andrzej Jasiewicz, Tomasz Kluz, Joanna Tomiczek-Szwiec, Ewa Kilar-Kobierzycka, Monika Siołek, Rafał Wiśniowski, Renata Posmyk, Joanna Jarkiewicz-Tretyn, Rodney Scott, Jan Lubiński
Format: Article
Language:English
Published: MDPI AG 2024-07-01
Series:Antioxidants
Subjects:
zinc
copper
blood levels
BRCA1
BRCA1 mutation
germline mutation
Online Access:https://www.mdpi.com/2076-3921/13/7/841

Internet

https://www.mdpi.com/2076-3921/13/7/841

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