miR-205-5p Mediated Downregulation of PTEN Contributes to Cisplatin Resistance in C13K Human Ovarian Cancer Cells

miR-205-5p Mediated Downregulation of PTEN Contributes to Cisplatin Resistance in C13K Human Ovarian Cancer Cells

Cisplatin resistance is a major cause of treatment failure in advanced ovarian cancer. The limited evidence shows the paradoxical regulation of miR-205 on chemotherapy resistance in cancer. Herein, we found that miR-205-5p was enormously increased in cisplatin-resistant C13K ovarian cancer cells com...

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Bibliographic Details
Main Authors: Xiaoyan Shi, Lan Xiao, Xiaolu Mao, Jinrong He, Yu Ding, Jin Huang, Caixia Peng, Zihui Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Genetics
Subjects:
miR-205-5p
PTEN
cisplatin resistance
ovarian cancer
AKT
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2018.00555/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2018.00555/full

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