A Comparative Genome-Wide Transcriptome Analysis of Glucocorticoid Responder and Non-Responder Primary Human Trabecular Meshwork Cells

A Comparative Genome-Wide Transcriptome Analysis of Glucocorticoid Responder and Non-Responder Primary Human Trabecular Meshwork Cells

<b>Aim:</b> To investigate genes and pathways involved in differential glucocorticoid (GC) responsiveness in human trabecular meshwork (HTM) cells using RNA sequencing. <b>Methods:</b> Using paired human donor eyes, human organ-cultured anterior segment (HOCAS) was establishe...

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Bibliographic Details
Main Authors: Kandasamy Kathirvel, Ravinarayanan Haribalaganesh, Ramasamy Krishnadas, Veerappan Muthukkaruppan, Colin E. Willoughby, Devarajan Bharanidharan, Srinivasan Senthilkumari
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Genes
Subjects:
glucocorticoid-induced ocular hypertension
human perfusion-cultured anterior segment
trabecular meshwork cells
gene expression
RNA-seq
candidate genes
Online Access:https://www.mdpi.com/2073-4425/13/5/882

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https://www.mdpi.com/2073-4425/13/5/882

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