Natural selection of human embryos: decidualizing endometrial stromal cells serve as sensors of embryo quality upon implantation.

Pregnancy is widely viewed as dependent upon an intimate dialogue, mediated by locally secreted factors between a developmentally competent embryo and a receptive endometrium. Reproductive success in humans is however limited, largely because of the high prevalence of chromosomally abnormal preimpla...

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Bibliographic Details
Main Authors: Gijs Teklenburg, Madhuri Salker, Mariam Molokhia, Stuart Lavery, Geoffrey Trew, Tepchongchit Aojanepong, Helen J Mardon, Amali U Lokugamage, Raj Rai, Christian Landles, Bernard A J Roelen, Siobhan Quenby, Ewart W Kuijk, Annemieke Kavelaars, Cobi J Heijnen, Lesley Regan, Jan J Brosens, Nick S Macklon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2858159?pdf=render